Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101167227Heat shock protein 12A. (670 aa)    
Predicted Functional Partners:
hspa9
Heat shock protein 9; Belongs to the heat shock protein 70 family.
   
 0.959
hspa13
Heat shock protein 70 family, member 13.
     
 0.939
hspa5
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.929
hspa4l
Heat shock protein 4 like.
   
 0.915
hspa4
Heat shock protein 4b.
   
 0.881
gak
Cyclin G associated kinase.
   
 0.837
LOC101166977
Heat shock protein 4a.
   
 0.831
LOC100125490
Uncharacterized protein; Belongs to the heat shock protein 70 family.
     
 0.793
hspe1
10 kDa heat shock protein, mitochondrial; Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per [...]
  
 
 0.781
akap12
A kinase (PRKA) anchor protein 12b.
    
 
 0.771
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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