Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
xpnpep2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound; Belongs to the peptidase M24B family. (672 aa)    
Predicted Functional Partners:
pitrm1
Pitrilysin metallopeptidase 1.
   
 
 0.767
wwc3
WWC family member 3.
  
  
 0.719
LOC101164137
Uncharacterized protein.
      
 0.651
jph1
Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
      
 0.651
jph2
Junctophilin 2.
      
 0.651
jph3
Junctophilin 3.
      
 0.651
BOLA2
BolA family member 2; Belongs to the BolA/IbaG family.
   
 
 0.618
mto1
Mitochondrial tRNA translation optimization 1.
   
 
 0.605
prep
Prolyl endopeptidase.
  
 
 0.604
supt7l
SPT7 like, STAGA complex gamma subunit.
      
 0.599
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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