Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2L747_ORYLAHistone H2A; Belongs to the histone H2A family. (130 aa)    
Predicted Functional Partners:
LOC101155571
Histone H2B; Belongs to the histone H2B family.
 
 0.837
LOC101155571-2
Histone H2B 1/2.
 
 0.837
LOC101155571-3
Histone H2B 1/2.
 
 0.837
LOC101155571-4
Histone H2B 1/2.
 
 0.821
ENSORLP00000045626
Histone H2B; Belongs to the histone H2B family.
 
 0.810
ENSORLP00000038070
Zgc:171759; Belongs to the histone H2B family.
  
 0.787
H2L736_ORYLA
Histone H2B; Belongs to the histone H2B family.
 
 0.786
ENSORLP00000042896
annotation not available
 
 0.786
rps27a
Ribosomal protein S27a.
   
 0.700
LOC101155824
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.650
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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