Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
vps45Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family. (570 aa)    
Predicted Functional Partners:
rbsn
Rabenosyn, RAB effector.
    
 0.999
stx16
Syntaxin 16; Belongs to the syntaxin family.
    
 
 0.984
vti1a
Vesicle transport through interaction with t-SNAREs 1A.
   
 
 0.983
vps18
VPS18 core subunit of CORVET and HOPS complexes.
    
 0.942
vti1b
Vesicle transport through interaction with t-SNAREs 1B.
   
 
 0.938
cog4
Component of oligomeric golgi complex 4.
   
 
 0.907
cog6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 0.906
mto1
Mitochondrial tRNA translation optimization 1.
 
      0.900
rab5c
RAB5C, member RAS oncogene family.
    
 0.892
LOC101159835
RAB5A, member RAS oncogene family, a.
    
 0.892
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.