STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vps45Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family. (570 aa)    
Predicted Functional Partners:
rbsn
Rabenosyn, RAB effector.
    
 0.998
stx16
Syntaxin 16; Belongs to the syntaxin family.
    
 
 0.993
vti1a
Vesicle transport through interaction with t-SNAREs 1A.
   
 
 0.932
vti1b
Vesicle transport through interaction with t-SNAREs 1B.
   
 
 0.920
LOC101172966
Syntaxin 6; Belongs to the syntaxin family.
    
 
 0.902
stx10
Syntaxin 10.
    
 
 0.902
mto1
Mitochondrial tRNA translation optimization 1.
 
      0.900
cog6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 0.880
vps18
VPS18 core subunit of CORVET and HOPS complexes.
    
 0.875
vps16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
   
 0.848
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.