Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101168730Homeobox domain-containing protein. (229 aa)    
Predicted Functional Partners:
pou1f1
POU domain protein.
    
 0.903
furin
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
      
 0.716
ghrh
Growth hormone releasing hormone.
      
 0.623
lhx3
Uncharacterized protein.
   
 0.606
lhx4
LIM homeobox 4.
   
 0.606
LOC101170553
NME/NM23 family member 8; Belongs to the NDK family.
    
   0.600
prl
Prolactin 2.
      
 0.580
LOC101172582
Prolactin.
      
 0.580
ENSORLP00000026554
Uncharacterized protein.
    
 0.577
fshb
Cys_knot domain-containing protein.
   
 
 0.570
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (20%) [HD]