Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
pus10Pseudouridine synthase 10. (535 aa)    
Predicted Functional Partners:
abitram
Actin binding transcription modulator.
    
   0.926
pus7
Pseudouridine synthase 7.
   
  
 0.783
trmt5
tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.
   
  
 0.780
pus7l
Pseudouridine synthase 7 like.
   
  
 0.779
pus1
Pseudouridine synthase 1.
   
  
 0.761
trmt12
tRNA methyltransferase 12 homolog.
   
  
 0.760
trub2
TruB pseudouridine (psi) synthase family member 2.
   
  
 0.732
rpusd1
RNA pseudouridine synthase domain containing 1.
      
 0.730
pus3
Pseudouridylate synthase 3.
   
  
 0.730
dkc1
Dyskeratosis congenita 1, dyskerin.
   
  
 0.728
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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