STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spry4Sprouty homolog 4 (Drosophila). (378 aa)    
Predicted Functional Partners:
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.765
LOC101163758
Uncharacterized protein.
    
 0.765
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase.
    
 0.765
LOC101158476
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.765
dusp6
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
   
  
 0.670
grb2
Growth factor receptor-bound protein 2b.
    
 0.610
il17rd
Interleukin 17 receptor D.
      
 0.578
LOC101165394
GRB2 related adaptor protein 2a.
    
 0.567
LOC101166194
GRB2 related adaptor protein b.
    
 0.567
LOC101160815
GRB2 related adaptor protein a.
    
 0.567
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.