denr protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

denr

Density-regulated protein; Belongs to the DENR family. (186 aa)

Predicted Functional Partners:

mcts1

0.993

fau

0.991

LOC101173816

0.944

abce1

0.942

eif2s2

0.939

rps3

0.935

eif3j

0.933

eif5

0.932

eif3g

0.931

rps25

0.920

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101173816	abce1	ENSORLP00000003034	ENSORLP00000038338	Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	ATP-binding cassette, sub-family E (OABP), member 1.	0.903
LOC101173816	denr	ENSORLP00000003034	ENSORLP00000001850	Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	Density-regulated protein; Belongs to the DENR family.	0.944
LOC101173816	eif2s2	ENSORLP00000003034	ENSORLP00000004417	Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	Eukaryotic translation initiation factor 2, subunit 2 beta.	0.997
LOC101173816	eif3g	ENSORLP00000003034	ENSORLP00000007040	Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.	0.997
LOC101173816	eif3j	ENSORLP00000003034	ENSORLP00000007846	Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.995
LOC101173816	eif5	ENSORLP00000003034	ENSORLP00000022443	Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	Eukaryotic translation initiation factor 5.	0.986
LOC101173816	fau	ENSORLP00000003034	ENSORLP00000018903	Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	40S ribosomal protein S30.	0.995
LOC101173816	rps25	ENSORLP00000003034	ENSORLP00000016402	Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.995
LOC101173816	rps3	ENSORLP00000003034	ENSORLP00000000748	Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.	0.999
abce1	LOC101173816	ENSORLP00000038338	ENSORLP00000003034	ATP-binding cassette, sub-family E (OABP), member 1.	Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.903
abce1	denr	ENSORLP00000038338	ENSORLP00000001850	ATP-binding cassette, sub-family E (OABP), member 1.	Density-regulated protein; Belongs to the DENR family.	0.942
abce1	eif2s2	ENSORLP00000038338	ENSORLP00000004417	ATP-binding cassette, sub-family E (OABP), member 1.	Eukaryotic translation initiation factor 2, subunit 2 beta.	0.876
abce1	eif3g	ENSORLP00000038338	ENSORLP00000007040	ATP-binding cassette, sub-family E (OABP), member 1.	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.	0.900
abce1	eif3j	ENSORLP00000038338	ENSORLP00000007846	ATP-binding cassette, sub-family E (OABP), member 1.	Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.988
abce1	eif5	ENSORLP00000038338	ENSORLP00000022443	ATP-binding cassette, sub-family E (OABP), member 1.	Eukaryotic translation initiation factor 5.	0.949
abce1	fau	ENSORLP00000038338	ENSORLP00000018903	ATP-binding cassette, sub-family E (OABP), member 1.	40S ribosomal protein S30.	0.990
abce1	mcts1	ENSORLP00000038338	ENSORLP00000041643	ATP-binding cassette, sub-family E (OABP), member 1.	Malignant T-cell-amplified sequence.	0.473
abce1	rps25	ENSORLP00000038338	ENSORLP00000016402	ATP-binding cassette, sub-family E (OABP), member 1.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.878
abce1	rps3	ENSORLP00000038338	ENSORLP00000000748	ATP-binding cassette, sub-family E (OABP), member 1.	Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.	0.922
denr	LOC101173816	ENSORLP00000001850	ENSORLP00000003034	Density-regulated protein; Belongs to the DENR family.	Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.944