Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Snx1Sorting nexin 1b. (305 aa)    
Predicted Functional Partners:
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.947
snx5
Sorting nexin 5.
   
 0.945
snx2
Sorting nexin 2.
  
  
0.911
LOC101163736
Sorting nexin 1a.
  
  
 
0.901
snx6
Sorting nexin; Involved in several stages of intracellular trafficking.
   
0.895
vps26a
VPS26, retromer complex component A.
   
 
 0.872
vps26b
VPS26, retromer complex component B.
   
 
 0.855
LOC101164612
PX domain-containing protein.
   
 
 0.717
snx4
Sorting nexin 4.
   
 
 0.717
igf2r
Insulin-like growth factor 2 receptor.
    
 0.695
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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