Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sbno1Strawberry notch homolog 1 (Drosophila). (1402 aa)    
Predicted Functional Partners:
LOC101171885
Interleukin 22 receptor, alpha 2.
      
 0.631
HDAC3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
      
 0.498
H2MTB4_ORYLA
Syntrophin, gamma 2.
      
 0.498
nol8
Nucleolar protein 8.
      
 0.498
sox5
HMG box domain-containing protein.
      
 0.481
CDK2AP1
Uncharacterized protein.
 
    
 0.476
LOC101162323
Galactose-3-O-sulfotransferase 4.
      
 0.464
ttc26
Tetratricopeptide repeat domain 26.
      
 0.463
LOC101155279
AT rich interactive domain 5A (MRF1-like).
   
  
 0.406
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (14%) [HD]