Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pcsk9Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (642 aa)    
Predicted Functional Partners:
pcsk2
Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family.
      
 0.941
LOC101167610
Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor.
    
 0.852
vldlr
Very low density lipoprotein receptor.
    
 0.839
LOC101167327
FAM20C golgi associated secretory pathway kinase.
    
 0.830
LOC101161779
Low density lipoprotein receptor b.
    
 0.830
LOC101163577
FAM20C golgi associated secretory pathway kinase a.
    
 0.830
LOC101174135
Uncharacterized protein.
    
 0.830
LOC101166361
Uncharacterized protein.
    
 0.830
ENSORLP00000037127
Uncharacterized protein.
    
 0.830
LOC111947820
Uncharacterized protein.
    
 0.830
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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