Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
os9OS9 endoplasmic reticulum lectin. (669 aa)    
Predicted Functional Partners:
sel1l
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 0.980
derl2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 0.970
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 0.945
syvn1
Synovial apoptosis inhibitor 1, synoviolin.
   
 0.909
vcp
Valosin containing protein; Belongs to the AAA ATPase family.
   
 0.906
amfr
Autocrine motility factor receptor b.
   
 0.895
spata5l1
Spermatogenesis associated 5-like 1.
   
 0.883
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 
 0.865
LOC101159283
Si:dkey-24p1.6.
   
 0.856
LOC101170338
Uncharacterized protein.
   
 0.856
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (12%) [HD]