Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101157756Cytochrome b-245, beta polypeptide (chronic granulomatous disease). (565 aa)    
Predicted Functional Partners:
ncf1
Neutrophil cytosolic factor 1.
   
 0.997
LOC101170577
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
   
 0.992
ncf4
Neutrophil cytosolic factor 4.
   
 0.991
nox4
FAD-binding FR-type domain-containing protein.
  
 
0.967
ncf2
Neutrophil cytosolic factor 2.
   
 0.948
nox5
NADPH oxidase, EF-hand calcium binding domain 5.
     
0.921
duox1
Dual oxidase.
     
0.913
LOC101168078
Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.
    
 0.913
LOC101159287
Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2.
   
 0.907
LOC101168093
Protein kinase domain-containing protein.
    
 0.906
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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