Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101158472VRK serine/threonine kinase 2. (544 aa)    
Predicted Functional Partners:
ankle2
Ankyrin repeat and LEM domain containing 2.
   
 0.964
LOC101171770
Uncharacterized protein.
    
 0.859
banf1
Barrier to autointegration factor 1.
    
 0.859
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.
   
 
 0.763
ltv1
LTV1 ribosome biogenesis factor.
    
 0.758
riok2
RIO domain-containing protein.
   
 0.754
bysl
Bystin-like.
    
 0.747
tsr1
TSR1 ribosome maturation factor.
    
 0.745
nob1
NIN1 (RPN12) binding protein 1 homolog.
    
 0.716
golga3
Golgin A3.
    
 0.704
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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