STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
p4hbProtein disulfide-isomerase. (511 aa)    
Predicted Functional Partners:
LOC101167922
Endoplasmic reticulum oxidoreductase alpha.
   
 0.986
ero1b
Endoplasmic reticulum oxidoreductase beta.
   
 0.986
hspa5
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.949
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.926
mttp
Microsomal triglyceride transfer protein.
    
 0.882
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
  
0.877
LOC101160304
Calreticulin.
   
 0.862
LOC101162115
Calreticulin.
   
 0.862
LOC101169735
Calreticulin.
   
 0.862
p4ha3
Prolyl 4-hydroxylase, alpha polypeptide III.
   
 0.835
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.