Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101166137EGF-like domain-containing protein. (154 aa)    
Predicted Functional Partners:
egfr
Receptor protein-tyrosine kinase.
    
 0.985
LOC101169984
Receptor protein-tyrosine kinase.
    
 0.972
erbb4
Receptor protein-tyrosine kinase.
    
 0.966
LOC101165379
Receptor protein-tyrosine kinase.
    
 0.966
LOC101155207
Betacellulin, epidermal growth factor family member.
     
 0.937
LOC101165892
EGF-like domain-containing protein.
     
 0.922
erbb3
Protein kinase domain-containing protein.
    
 0.883
LOC101174230
Receptor protein-tyrosine kinase.
    
 0.883
LOC101172978
Erb-b2 receptor tyrosine kinase 3b.
    
 0.883
egf
Epidermal growth factor.
    
 0.849
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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