Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101170772S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (390 aa)    
Predicted Functional Partners:
amd1
S-adenosylmethionine decarboxylase proenzyme.
   
 
 0.969
LOC101175580
Betaine-homocysteine methyltransferase; Involved in the regulation of homocysteine metabolism.
  
 
 0.968
mtr
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.955
tat
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
  
 0.954
LOC101164391
Zgc:172121.
  
 
 0.953
LOC101157623
Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.
  
 
 0.947
gnmt
Glycine N-methyltransferase.
   
 
 0.931
mat2b
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
  
 0.911
LOC101161073
Amine oxidase.
    
 0.807
mthfr
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.781
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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