Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sox2SOX3 protein. (300 aa)    
Predicted Functional Partners:
LOC100049520
POU domain protein.
    
 0.925
nanog
Homeobox domain-containing protein.
    
 0.905
sall4
Spalt-like transcription factor 4.
   
 0.787
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.750
klf4
Kruppel-like factor 4.
   
 0.720
otx2
Homeobox domain-containing protein.
   
 0.672
LOC101166663
Kruppel-like factor 17.
    
 0.655
pax6
Paired box protein Pax-6; May be a transcription factor with important functions in eye and nasal development; Belongs to the paired homeobox family.
   
 0.646
fgf8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.635
prdm14
PR domain containing 14.
    
 0.623
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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