Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC101174825Fibroblast growth factor receptor substrate 3. (608 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.942
LOC101172160
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.840
ptpn6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.840
ptpn11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.840
sos2
Son of sevenless homolog 2 (Drosophila).
   
 0.820
sos1
Son of sevenless homolog 1 (Drosophila).
   
 0.820
fgfr2
Fibroblast growth factor receptor.
    
 0.776
ret
Ret proto-oncogene receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.774
fgfr1
Fibroblast growth factor receptor.
    
 0.770
LOC100049521
Fibroblast growth factor receptor 4.
    
 0.744
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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