STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
snx12Sorting nexin 12. (162 aa)    
Predicted Functional Partners:
vps26b
VPS26, retromer complex component B.
   
 0.965
vps26a
VPS26, retromer complex component A.
   
 0.961
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.933
snx3
Sorting nexin 3.
  
  
 
0.901
wls
Wnt ligand secretion mediator.
    
 0.760
usp10
Ubiquitin carboxyl-terminal hydrolase.
    
 0.703
hgs
Hepatocyte growth factor-regulated tyrosine kinase substrate.
    
 
 0.622
LOC101163736
Sorting nexin 1a.
   
0.588
snx2
Sorting nexin 2.
   
0.588
snx17
Sorting nexin 17.
    
 
 0.522
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.