STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101160237Activity-dependent neuroprotector homeobox b. (1048 aa)    
Predicted Functional Partners:
zmym2
Zinc finger, MYM-type 2.
   
 
 0.765
trip12
Thyroid hormone receptor interactor 12.
   
  
 0.756
chd8
Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]
   
 
 0.754
LOC101174845
Chromodomain helicase DNA binding protein 4a.
   
 
 0.707
LOC101167742
Chromodomain helicase DNA binding protein 3.
   
 
 0.707
aire
Autoimmune regulator.
   
 
 0.707
chd5
Uncharacterized protein.
   
 
 0.707
chd4
Uncharacterized protein.
   
 
 0.707
ENSORLP00000033531
CHDCT2 domain-containing protein.
   
 
 0.707
CBX1
Uncharacterized protein.
    
 
 0.695
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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