Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC101175634Myocilin. (570 aa)    
Predicted Functional Partners:
wdr36
WD repeat domain 36.
      
 0.694
hce
High choriolytic enzyme 1; Participates in the breakdown of the egg envelope, which is derived from the egg extracellular matrix, at the time of hatching. Thus allowing the newly hatched fish to swim free. HCE binds tightly to the egg envelope while it exerts the choriolytic swelling action.
    
 0.605
optn
Optineurin.
      
 0.535
MYL2
Myosin, light chain 2b, regulatory, cardiac, slow.
    
 
 0.516
MYL2-2
Myosin light chain 2.
    
 
 0.516
LOC101159216
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
      
 0.498
il17rel
IL17_R_N domain-containing protein.
      
 0.486
LOC101167732
Microfibril associated protein 5.
   
  
 0.466
LOC101159264
Reprimo-like.
      
 0.462
telo2
TEL2, telomere maintenance 2, homolog (S. cerevisiae).
      
 0.462
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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