Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ibtkInhibitor of Bruton agammaglobulinemia tyrosine kinase. (1329 aa)    
Predicted Functional Partners:
Pop7
Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
    
   0.962
H2MR55_ORYLA
Ribonuclease P/MRP 25 subunit-like.
    
 
 0.954
LOC101172920
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.926
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.926
dnajc17
DnaJ (Hsp40) homolog, subfamily C, member 17.
      
 0.914
LOC101158762
Alba domain-containing protein.
    
   0.766
irak1bp1
Interleukin-1 receptor-associated kinase 1 binding protein 1.
      
 0.748
cul1
Cullin 1b; Belongs to the cullin family.
   
 0.744
eif4a2
Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family.
    
   0.723
LOC101155548
Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family.
    
   0.723
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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