Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ube3dUbiquitin protein ligase E3D. (396 aa)    
Predicted Functional Partners:
cpsf3
Cleavage and polyadenylation specific factor 3.
    
 
 0.957
ube2c
Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.883
memo1
Mediator of cell motility 1.
    
   0.869
ENSORLP00000030299
DWNN domain-containing protein.
    
 0.849
rbbp6
RING-type domain-containing protein.
    
 0.849
LOC101160962
Uncharacterized protein.
    
 0.849
LOC101173088
Cytochrome b5 reductase 4.
      
 0.710
LOC101160424
ADNP homeobox 2b.
      
 0.599
trip12
Thyroid hormone receptor interactor 12.
     
  0.582
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
    
 
 0.573
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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