Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COL8A1Collagen type VIII alpha 1 chain. (769 aa)    
Predicted Functional Partners:
Col27a1
LAM_G_DOMAIN domain-containing protein.
 
   
 0.625
nit2
Nitrilase family, member 2.
      
 0.611
nt5dc1
5'-nucleotidase domain containing 1.
      
 0.609
col8a2
Collagen, type VIII, alpha 2.
     
  0.577
col6a1
Collagen, type VI, alpha 1.
  
0.545
LOC101161734
Kelch-like family member 4.
    
 0.539
spata2
Spermatogenesis associated 2.
      
 0.527
ENSORLP00000027031
Uncharacterized protein.
  
     0.524
fstl1
Follistatin-like 1b.
      
 0.523
thbs2
Thrombospondin 2a.
    
 0.512
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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