STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLE3TLE family member 3, transcriptional corepressor. (783 aa)    
Predicted Functional Partners:
smad3
Mothers against decapentaplegic homolog.
    
 
 0.678
lef1
Lymphoid enhancer-binding factor 1.
    
 0.618
tcf7
Transcription factor 7.
    
 0.618
tcf7l1
HMG box domain-containing protein.
    
 0.610
LOC111948314
HMG box domain-containing protein.
    
 0.610
tcf7l2
Transcription factor 7 like 2.
    
 0.610
smad6
Mothers against decapentaplegic homolog.
      
 0.581
KIF23
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.569
LOC101170342
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.569
en1
Homeobox protein engrailed-like.
    
 
 0.558
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.