uaca protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

uaca

Uveal autoantigen with coiled-coil domains and ankyrin repeats b. (1384 aa)

Predicted Functional Partners:

polr3b

0.723

casp9

0.695

usp48

0.631

dennd6b

0.604

dnajc5g

0.588

vcp

0.560

pik3c3

0.559

apaf1

0.554

fastkd3

0.537

pdcd7

0.526

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
apaf1	casp9	ENSORLP00000019346	ENSORLP00000040536	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.999
apaf1	uaca	ENSORLP00000019346	ENSORLP00000002483	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uveal autoantigen with coiled-coil domains and ankyrin repeats b.	0.554
casp9	apaf1	ENSORLP00000040536	ENSORLP00000019346	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.999
casp9	pik3c3	ENSORLP00000040536	ENSORLP00000034727	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.503
casp9	uaca	ENSORLP00000040536	ENSORLP00000002483	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Uveal autoantigen with coiled-coil domains and ankyrin repeats b.	0.695
dennd6b	dnajc5g	ENSORLP00000025487	ENSORLP00000010868	DENN/MADD domain containing 6B.	DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a.	0.491
dennd6b	uaca	ENSORLP00000025487	ENSORLP00000002483	DENN/MADD domain containing 6B.	Uveal autoantigen with coiled-coil domains and ankyrin repeats b.	0.604
dnajc5g	dennd6b	ENSORLP00000010868	ENSORLP00000025487	DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a.	DENN/MADD domain containing 6B.	0.491
dnajc5g	uaca	ENSORLP00000010868	ENSORLP00000002483	DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a.	Uveal autoantigen with coiled-coil domains and ankyrin repeats b.	0.588
fastkd3	pik3c3	ENSORLP00000036657	ENSORLP00000034727	FAST kinase domains 3.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.494
fastkd3	polr3b	ENSORLP00000036657	ENSORLP00000013878	FAST kinase domains 3.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.508
fastkd3	uaca	ENSORLP00000036657	ENSORLP00000002483	FAST kinase domains 3.	Uveal autoantigen with coiled-coil domains and ankyrin repeats b.	0.537
pdcd7	uaca	ENSORLP00000000807	ENSORLP00000002483	Programmed cell death 7.	Uveal autoantigen with coiled-coil domains and ankyrin repeats b.	0.526
pik3c3	casp9	ENSORLP00000034727	ENSORLP00000040536	Phosphatidylinositol 3-kinase catalytic subunit type 3.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.503
pik3c3	fastkd3	ENSORLP00000034727	ENSORLP00000036657	Phosphatidylinositol 3-kinase catalytic subunit type 3.	FAST kinase domains 3.	0.494
pik3c3	polr3b	ENSORLP00000034727	ENSORLP00000013878	Phosphatidylinositol 3-kinase catalytic subunit type 3.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.530
pik3c3	uaca	ENSORLP00000034727	ENSORLP00000002483	Phosphatidylinositol 3-kinase catalytic subunit type 3.	Uveal autoantigen with coiled-coil domains and ankyrin repeats b.	0.559
polr3b	fastkd3	ENSORLP00000013878	ENSORLP00000036657	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	FAST kinase domains 3.	0.508
polr3b	pik3c3	ENSORLP00000013878	ENSORLP00000034727	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.530
polr3b	uaca	ENSORLP00000013878	ENSORLP00000002483	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uveal autoantigen with coiled-coil domains and ankyrin repeats b.	0.723