Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
npas4Neuronal PAS domain protein 4a. (930 aa)    
Predicted Functional Partners:
arnt
Aryl hydrocarbon receptor nuclear translocator.
    
 0.969
LOC101159313
Aryl hydrocarbon receptor nuclear translocator-like 1a.
    
 0.758
ARNTL2
Aryl hydrocarbon receptor nuclear translocator like 2.
    
 0.755
LOC101174183
Aryl hydrocarbon receptor nuclear translocator-like 2.
    
 0.755
LOC101154928
Necdin-like 2.
    
 0.701
CLOCK
Clock circadian regulator a.
    
 0.695
fosb
FBJ murine osteosarcoma viral oncogene homolog B.
   
 
 0.676
egr1
Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.
   
  
 0.668
utp15
UTP15 small subunit processome component.
   
    0.660
c-fos
BZIP domain-containing protein.
   
 
 0.642
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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