Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
hic2Hypermethylated in cancer 2. (584 aa)    
Predicted Functional Partners:
sirt1
Deacetylase sirtuin-type domain-containing protein.
    
 
 0.800
nudcd1
NudC domain containing 1.
    
   0.627
LOC101169703
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.585
ube2i
Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.585
cnksr1
Connector enhancer of kinase suppressor of Ras 1.
     
 0.565
mia3
Uncharacterized protein.
    
 0.554
mta1
Metastasis associated 1.
    
 0.541
sumo1
Small ubiquitin-related modifier.
    
 0.512
zbtb8a
Zinc finger and BTB domain containing 8A.
    
   0.508
LOC101155036
Protein inhibitor of activated STAT, 2.
    
  0.495
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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