Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2L9V8_ORYLAUncharacterized protein. (649 aa)    
Predicted Functional Partners:
fancm
Uncharacterized protein.
    
 0.749
wdr73
Uncharacterized protein.
    
  0.507
rbbp4
Retinoblastoma binding protein 4.
    
  0.507
LOC101156710
Retinoblastoma binding protein 4, like.
    
  0.507
med14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.501
LOC101170553
NME/NM23 family member 8; Belongs to the NDK family.
    
 0.494
ino80d
INO80 complex subunit Da.
    
  0.469
med12
Mediator complex subunit 12.
    
  0.469
col22a1
Collagen, type XXII, alpha 1.
    
  0.466
mrps11
Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family.
   
  0.456
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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