STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plpbpPyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6. (291 aa)    
Predicted Functional Partners:
lacc1
Laccase (multicopper oxidoreductase) domain containing 1.
  
  
 0.905
LOC101171384
Pyridoxal (pyridoxine, vitamin B6) kinase b.
  
  
 0.733
LOC101155341
Pyridoxal (pyridoxine, vitamin B6) kinase a.
  
  
 0.733
aadat
Aminoadipate aminotransferase.
  
 
 0.715
hspe1
10 kDa heat shock protein, mitochondrial; Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per [...]
     
 0.692
suox
Sulfite oxidase.
     
 0.690
cth
Cystathionase (cystathionine gamma-lyase), like.
  
  
 0.676
pnpo
Pyridoxamine 5'-phosphate oxidase.
      
 0.668
pipox
Pipecolic acid oxidase.
    
 0.614
mrpl36
Ribosomal protein; Belongs to the bacterial ribosomal protein bL36 family.
  
    0.602
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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