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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
map2k5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (445 aa)    
Predicted Functional Partners:
LOC101157651
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.980
map3k2
Mitogen-activated protein kinase kinase kinase 2.
  
0.976
ksr2
Kinase suppressor of ras 2.
   
 0.849
ksr1
Kinase suppressor of ras 1a.
   
0.849
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
   
0.822
araf
A-Raf proto-oncogene, serine/threonine kinase.
   
0.822
braf
B-Raf proto-oncogene, serine/threonine kinase.
   
0.822
LOC101159747
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.815
LOC101162905
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.815
LOC101156127
Mitogen-activated protein kinase kinase kinase 22.
  
0.777
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.