Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
map2k5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (445 aa)    
Predicted Functional Partners:
LOC101157651
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.985
map3k2
Mitogen-activated protein kinase kinase kinase 2.
  
 
0.980
sqstm1
Sequestosome 1.
    
 
 0.905
ksr2
Kinase suppressor of ras 2.
   
 0.861
ksr1
Kinase suppressor of ras 1a.
   
 0.861
LOC101159747
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.860
LOC101162905
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.860
lamtor3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
   
 0.845
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
   
 0.827
araf
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.827
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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