Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
olgc8Guanylate cyclase. (859 aa)    
Predicted Functional Partners:
nppc
C-type natriuretic peptide 4; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
    
 0.984
entpd1
Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family.
   
 
 0.917
npr2
Guanylate cyclase.
  
  
 
0.903
nudt2
Nudix (nucleoside diphosphate linked moiety X)-type motif 2.
     
  0.900
cnp-1
C-type natriuretic peptide 1; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
     
  0.900
cnp-3
C-type natriuretic peptide 3; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
     
  0.900
mocs1
Molybdenum cofactor synthesis 1.
   
 
 0.808
LOC101161367
GTP cyclohydrolase 2.
     
 0.802
pde6g
Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.
     
 0.769
PDE3A
Phosphodiesterase.
   
 0.768
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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