close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105356506Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family. (366 aa)    
Predicted Functional Partners:
LOC101173499
Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
   
 0.972
LOC101160349
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 0.964
LOC101157008
Cytochrome P450, family 8, subfamily B, polypeptide 2; Belongs to the cytochrome P450 family.
   
 0.964
LOC101175316
Aldo_ket_red domain-containing protein.
  
 
 0.908
AKR1D1
Aldo-keto reductase family 1 member D1.
  
 
 0.908
LOC101172816
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family.
  
  
 
0.900
fau
40S ribosomal protein S30.
   
 0.882
H2N0C8_ORYLA
Cytochrome P450, family 51; Belongs to the cytochrome P450 family.
   
 0.874
fdft1
Farnesyl-diphosphate farnesyltransferase 1.
  
 
 0.858
sqle
Squalene epoxidase a.
   
 
 0.856
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (30%) [HD]