Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ccdc47Coiled-coil domain containing 47. (504 aa)    
Predicted Functional Partners:
tmco1
Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling.
    
 
 0.947
tmem147
Transmembrane protein 147.
   
 
 0.937
ncln
Nicalin.
    
 
 0.932
LOC101155768
Translocating chain-associated membrane protein; Belongs to the TRAM family.
    
 
 0.927
wdr83os
WD repeat domain 83 opposite strand.
    
 
 0.912
sec61b
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 
 0.869
emc2
ER membrane protein complex subunit 2.
   
 
 0.864
sec61a1
Plug_translocon domain-containing protein.
   
 
 0.861
LOC101169601
Plug_translocon domain-containing protein.
   
 
 0.861
rpl32
Ribosomal protein L32.
   
   0.835
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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