Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
barhl2BarH-like homeobox 2. (361 aa)    
Predicted Functional Partners:
LOC101160967
Iroquois homeobox 7.
    
 
 0.653
foxn4
Forkhead box N4.
   
 0.609
bhlhe22
Basic helix-loop-helix family, member e22.
   
  
 0.609
pou4f2
POU domain protein.
  
  
 0.601
C1orf146
Chromosome 1 open reading frame 146.
      
 0.600
ptf1a
Pancreas associated transcription factor 1a.
      
 0.574
lhx5
LIM homeobox 5.
   
 0.528
LOC101174213
Zinc finger protein 503.
      
 0.516
nr2e1
Nuclear receptor subfamily 2 group E member 1; Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be involved in the regulation of early eye development.
    
 
 0.470
znf503
Zinc finger protein 503.
      
 0.465
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (12%) [HD]