Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cfiComplement factor I; Belongs to the peptidase S1 family. (654 aa)    
Predicted Functional Partners:
LOC101157860
Regulator of complement activation group 2 gene 2.
    
 0.922
ENSORLP00000027886
C-type lectin domain-containing protein.
   
 0.892
c5
Uncharacterized protein.
   
 0.881
serpinf2
SERPIN domain-containing protein; Belongs to the serpin family.
   
 0.794
c7
Complement component 7a.
   
  
 0.778
c4b
Uncharacterized protein.
   
 0.757
LOC110016646
Complement 4B (Chido blood group).
   
 0.757
c3-1
Uncharacterized protein.
   
 0.757
H2M6Q1_ORYLA
NTR domain-containing protein.
   
 0.757
H2MTY4_ORYLA
Uncharacterized protein.
   
 0.757
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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