Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hckTyrosine-protein kinase. (504 aa)    
Predicted Functional Partners:
tm9sf4
Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
      
 0.807
LOC101175223
Uncharacterized protein.
   
 0.726
grb2
Growth factor receptor-bound protein 2b.
   
 0.718
LOC101170140
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
 0.700
tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
   
 0.689
syk
Tyrosine-protein kinase.
   
 0.683
LOC101170171
Zeta chain of T cell receptor associated protein kinase 70.
   
 0.678
sos2
Son of sevenless homolog 2 (Drosophila).
    
 0.672
LOC101162652
FERM domain-containing protein.
 
 
 0.669
LOC101174926
Docking protein 2.
   
 0.668
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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