close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dtwd1DTW domain containing 1. (302 aa)    
Predicted Functional Partners:
mphosph10
U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family.
      
 0.573
dtwd2
DTW domain containing 2.
      
 0.564
tsr3
Probable ribosome biogenesis protein tsr3; Probable pre-rRNA processing protein involved in ribosome biogenesis.
      
 0.563
dus2
Dihydrouridine synthase 2.
      
 0.562
ebna1bp2
EBNA1 binding protein 2.
      
 0.558
dus4l
tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family.
      
 0.558
ccdc85c
Coiled-coil domain containing 85C.
      
 0.516
ENSORLP00000037368
Uncharacterized protein.
      
 0.516
spcs1
Signal peptidase complex subunit 1.
      
 0.483
fgf7
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
 
      0.441
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (30%) [HD]