Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
arhgap22Rho GTPase activating protein 22. (813 aa)    
Predicted Functional Partners:
LOC101175393
Macrophage stimulating 1 receptor a.
   
  0.513
met
MET proto-oncogene, receptor tyrosine kinase.
   
  0.513
mst1r
Macrophage stimulating 1 receptor b.
   
  0.513
meak7
MTOR associated protein, eak-7 homolog.
      
 0.498
sh2d5
SH2 domain containing 5.
      
 0.463
LOC101158957
RAB25, member RAS oncogene family a.
    
 0.455
rab25
RAB25, member RAS oncogene family b.
    
 0.455
coq5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).
      
 0.452
LOC105357330
Cadherin 3.
     
 0.446
Pitpnc1
Uncharacterized protein.
      
 0.442
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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