Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
meis1Meis homeobox 1 b. (388 aa)    
Predicted Functional Partners:
hoxa9
Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.
    
 
 0.807
LOC101164149
Teashirt zinc finger homeobox 3a.
   
 0.766
dlx3
Distal-less homeobox 3b.
    
 
 0.724
fam222a
Family with sequence similarity 222 member A.
    
   0.707
pbx1
Homeobox domain-containing protein.
   
 0.706
LOC101160104
Pre-B-cell leukemia homeobox 1b.
   
 0.706
LOC101159440
Pre-B-cell leukemia transcription factor 4.
   
 0.706
pbx3
Homeobox domain-containing protein.
   
 0.706
LOC101172525
Pre-B-cell leukemia homeobox 2.
   
 0.706
yap1
Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation.
    
 0.701
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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