STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
meis1Meis homeobox 1 b. (388 aa)    
Predicted Functional Partners:
pbx1
Homeobox domain-containing protein.
   
0.723
LOC101160104
Pre-B-cell leukemia homeobox 1b.
   
0.709
LOC101159440
Pre-B-cell leukemia transcription factor 4.
   
0.709
pbx3
Homeobox domain-containing protein.
   
0.709
LOC101172525
Pre-B-cell leukemia homeobox 2.
   
0.709
LOC101164149
Teashirt zinc finger homeobox 3a.
   
 0.705
LOC101175240
Homeobox B13a.
    
 
 0.628
tshz3
Teashirt zinc finger homeobox 3b.
   
 0.602
yap1
Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation.
    
 0.591
dlx3
Distal-less homeobox 3b.
    
 
 0.586
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.