STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRED2Sprouty related EVH1 domain containing 2. (464 aa)    
Predicted Functional Partners:
H2MJT0_ORYLA
Uncharacterized protein.
    
 0.822
Nf1
Uncharacterized protein.
    
 0.822
nek2
NIMA-related kinase 2.
    
 0.612
etaa1
Uncharacterized protein.
      
 0.590
CACNA1D
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
      
 0.583
Cacna1d
Calcium channel, voltage-dependent, L type, alpha 1D subunit, b.
      
 0.583
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
     
 0.559
hras
HRas proto-oncogene, GTPase a.
   
 0.552
LOC101154954
Zgc:55558.
   
 0.552
kras
GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation.
   
 0.552
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.