Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cxcr5Chemokine (C-X-C motif) receptor 5; Belongs to the G-protein coupled receptor 1 family. (361 aa)    
Predicted Functional Partners:
Cxcl13
SCY domain-containing protein.
    
 0.997
LOC101159348
Link domain-containing protein.
     
 0.893
ENSORLP00000036680
Ig-like domain-containing protein.
   
  
 0.844
cxcl12
Chemokine (C-X-C motif) ligand 12b; Belongs to the intercrine alpha (chemokine CxC) family.
    
 0.791
LOC101167049
CD40 ligand; Belongs to the tumor necrosis factor family.
   
  
 0.748
LOC101160820
SCY domain-containing protein.
    
 0.728
LOC100125525
Uncharacterized protein.
      
 0.722
batf
Basic leucine zipper transcription factor, ATF-like.
      
 0.721
LOC100125537
Uncharacterized protein.
      
 0.704
rag1
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]
      
 0.693
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (8%) [HD]