Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fgbFibrinogen beta chain. (498 aa)    
Predicted Functional Partners:
fga
Fibrinogen alpha chain.
   
0.999
LOC101170246
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.994
stil
SERPIN domain-containing protein; Belongs to the serpin family.
   
 0.966
mis12
MIS12 kinetochore complex component.
    
   0.936
LOC101168652
Alpha-2-HS-glycoprotein 2.
   
 0.934
ENSORLP00000043209
Alpha-1-microglobulin/bikunin precursor.
   
  
 0.892
serpind1
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.
   
 0.868
habp2
Uncharacterized protein.
   
 0.787
fn1
Fibronectin-1.
   
 0.781
serpinf2
SERPIN domain-containing protein; Belongs to the serpin family.
   
 
 0.718
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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