polb protein (Oryzias latipes) - STRING interaction network

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polb

DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (338 aa)

Predicted Functional Partners:

pnkp

0.999

lig3

0.998

xrcc1

0.998

apex1

0.996

lig1

0.991

parp1

0.990

neil1

0.988

tdp1

0.981

parp2

0.977

ENSORLP00000041372

0.970

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000041372	lig1	ENSORLP00000041372	ENSORLP00000003171	Uncharacterized protein.	DNA ligase.	0.474
ENSORLP00000041372	lig3	ENSORLP00000041372	ENSORLP00000029955	Uncharacterized protein.	DNA ligase.	0.988
ENSORLP00000041372	parp1	ENSORLP00000041372	ENSORLP00000017176	Uncharacterized protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.983
ENSORLP00000041372	parp2	ENSORLP00000041372	ENSORLP00000045298	Uncharacterized protein.	Poly [ADP-ribose] polymerase.	0.976
ENSORLP00000041372	pnkp	ENSORLP00000041372	ENSORLP00000019614	Uncharacterized protein.	Polynucleotide kinase 3'-phosphatase.	0.853
ENSORLP00000041372	polb	ENSORLP00000041372	ENSORLP00000003117	Uncharacterized protein.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.970
ENSORLP00000041372	tdp1	ENSORLP00000041372	ENSORLP00000018113	Uncharacterized protein.	Tyrosyl-DNA phosphodiesterase 1.	0.971
ENSORLP00000041372	xrcc1	ENSORLP00000041372	ENSORLP00000039866	Uncharacterized protein.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.988
apex1	lig1	ENSORLP00000015494	ENSORLP00000003171	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA ligase.	0.982
apex1	lig3	ENSORLP00000015494	ENSORLP00000029955	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA ligase.	0.752
apex1	neil1	ENSORLP00000015494	ENSORLP00000009122	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Nei-like DNA glycosylase 1.	0.679
apex1	parp1	ENSORLP00000015494	ENSORLP00000017176	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.772
apex1	parp2	ENSORLP00000015494	ENSORLP00000045298	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Poly [ADP-ribose] polymerase.	0.697
apex1	pnkp	ENSORLP00000015494	ENSORLP00000019614	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Polynucleotide kinase 3'-phosphatase.	0.837
apex1	polb	ENSORLP00000015494	ENSORLP00000003117	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.996
apex1	tdp1	ENSORLP00000015494	ENSORLP00000018113	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Tyrosyl-DNA phosphodiesterase 1.	0.814
apex1	xrcc1	ENSORLP00000015494	ENSORLP00000039866	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.943
lig1	ENSORLP00000041372	ENSORLP00000003171	ENSORLP00000041372	DNA ligase.	Uncharacterized protein.	0.474
lig1	apex1	ENSORLP00000003171	ENSORLP00000015494	DNA ligase.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.982
lig1	lig3	ENSORLP00000003171	ENSORLP00000029955	DNA ligase.	DNA ligase.	0.651

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