Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101170271Nerve growth factor receptor a (TNFR superfamily, member 16). (389 aa)    
Predicted Functional Partners:
LOC101164147
Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family.
    
 0.997
LOC101157368
Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.
    
 0.997
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.994
bdnf
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
    
 0.936
LOC101163518
Neurotrophin receptor associated death domain.
  
  
 
0.909
LOC101166088
Nerve growth factor receptor b.
  
 
 
0.909
LOC101172288
Amyloid beta (A4) precursor protein b.
    
 
 0.902
APP
Amyloid beta precursor protein.
    
 
 0.902
ripk2
Receptor-interacting serine-threonine kinase 2.
    
 0.901
LOC101169531
Sortilin.
    
 
 0.895
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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