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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101157139Retinal outer segment membrane protein 1b. (362 aa)    
Predicted Functional Partners:
LOC101163349
Retinal outer segment membrane protein 1a.
  
  
0.869
LOC105357406
Uncharacterized protein.
  
 
0.730
LOC101158810
Peripherin 2-like a.
  
 
0.729
LOC101171355
Uncharacterized protein.
  
 
0.728
prph2
Peripherin 2a (retinal degeneration, slow).
  
 
0.728
pax6
Paired box protein Pax-6; May be a transcription factor with important functions in eye and nasal development; Belongs to the paired homeobox family.
      
 0.678
H2LGY1_ORYLA
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
  
 0.676
glyr1
Glyoxylate reductase 1 homolog (Arabidopsis).
      
 0.610
grk7
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
   
  
 0.592
ccdc25
Coiled-coil domain containing 25.
      
 0.558
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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