Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
krt222Keratin 222; Belongs to the intermediate filament family. (531 aa)    
Predicted Functional Partners:
Unc79
Uncharacterized protein.
   
 0.706
LOC101167707
Keratin 5; Belongs to the intermediate filament family.
   
 0.653
LOC101172686
Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.
     
 0.618
mmp28
Matrix metallopeptidase 28.
     
 0.615
LOC101171028
Hyaluronan synthase 1.
    
 
 0.527
LOC101172978
Erb-b2 receptor tyrosine kinase 3b.
    
 
 0.509
cpsf1
Cleavage and polyadenylation specific factor 1.
    
  0.501
LOC101168366
Keratin 8; Belongs to the intermediate filament family.
   
 0.488
LOC101172973
Keratin 4; Belongs to the intermediate filament family.
   
 0.488
LOC101160447
RAN binding protein 2.
    
 0.474
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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