Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccr7Chemokine (C-C motif) receptor 7; Belongs to the G-protein coupled receptor 1 family. (407 aa)    
Predicted Functional Partners:
LOC101162278
Chemokine (C-C motif) ligand 25b.
   
 0.924
LOC101170597
SCY domain-containing protein.
     
  0.900
arhgef2
Rho/rac guanine nucleotide exchange factor (GEF) 2.
     
 0.545
sec11a
Signal peptidase complex catalytic subunit SEC11.
    
 0.539
LOC101157210
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
      
 0.524
LOC101168830
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
      
 0.524
LOC101167902
Tyrosine-protein kinase.
   
 0.509
akirin2
Akirin 2.
      
 0.503
a-sdf1a
Chemokine (C-X-C motif) ligand 12a; Belongs to the intercrine alpha (chemokine CxC) family.
    
 0.502
LOC100125525
Uncharacterized protein.
      
 0.498
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (18%) [HD]