Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aco2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)    
Predicted Functional Partners:
cs
Citrate synthase; Belongs to the citrate synthase family.
  
 0.999
H2MXI0_ORYLA
Isocitrate dehydrogenase (NAD(+)) 3 alpha.
  
 0.997
Mdh2
Malate dehydrogenase.
  
 0.996
LOC101173617
Malate synthase-like.
  
 0.995
LOC101171328
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.994
LOC101166704
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.994
idh3b
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.992
idh3g
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.992
LOC101156895
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.992
fh
Fumarate hydratase.
  
 0.988
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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